2011 Summit on Translational Bioinformatics

March 7, 2011 - March 9, 2011
Park 55 Hotel
San Francisco, CA

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  • AMIA 2010 Reviewers AMIA 2010 Reviewers
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    AMIA 2010 Reviewers

     

     

    Aarts, Jos

    Abraham, Joanna

    Abramson, Erika

    Acharya, Amit

    Ackerman, Michael

    Adam, Terrence Joseph

    Adida, Ben

    Afrin, Lawrence

    Agarwal, Shashank

    Agresta, Thomas

    Ahmed, Sara

    Albers, David J

    Alekseyenko, Alexander

    Alexander, Gregory L

    Aliferis, Constantin

    Alonso-Calvo, Ral

    Alterovitz, Gil

    Ambert, Kyle H

    Ammenwerth, Elske

    Anand, Vibha

    Ancker, Jessica S

    Anders, Shilo

    Anderson, Nicholas R

    Anderson, Nick

    Andreassen, Steen

    Anthony, Stephen

    Aphinyanaphongs, Yindalon

    Armijo, Dan

    Arnold, Corey

    Aronsky, Dominik

    Aronson, Alan R

    Ash, Joan S

    Aucoin, Nicole

    Avillach, Paul

    Bakken, Suzanne

    Baorto, David

    Barnes, Michael

    Bashyam, Vijayaraghavan

    Baum, Judith

    Bedrick, Steven

    Berhe, Solomon

    Berndt, Donald

    Berner, Eta S

    Bernstam, Elmer Victor

    Bhavnani, Suresh K

    Bitton, Asaf

    Bodenreider, Olivier

    Boren, Suzanne Austin

    Borlawsky, Tara

    Borsato, Emerson

    Bouhaddou, Omar

    Bousquet, C

    Boussadi, Abdelali

    Bowes, Watson

    Bowles, Kathryn Helene

    Boxwala, Aziz A

    Boyd, Andrew D

    Bradshaw, Richard

    Brandt, Cynthia

    Bray, Bruce E

    Brennan, Patricia Flatley

    Brinkley, James F

    Brixey, Juliana J

    Brown, Laura E

    Brown, Stuart

    Brownstein, John

    Buck, Michael D

    Buckeridge, David

    Burgun, Anita

    Butte, Atul

    Byrne, Colene Maree

    Cai, Zhaohui

    Campbell, Emily M

    Campion, Thomas Richmond

    Cantor, Michael N

    Cao, Hui

    Carter, John S

    Cato, Kenrick D

    Chang, Chee Fon

    Chapman, Brian E

    Chapman, Wendy W

    Chase, Herbert

    Chelico, John

    Chen, Yunan

    Cheung, Kei

    Chiang, Michael F

    Chute, Christopher G

    Cimino, James J

    Civan-Hartzler, Andrea L

    Co Jr, Manuel C

    Cohen, Aaron Michael

    Cohen, Kevin

    Cohen, Trevor

    Collins, Sarah Anne

    Conway, Mike

    Coonan, Kevin

    Cooper, Gregory F

    Cornet, Ronald

    Courtney, Karen L

    Covvey, Dominic Joseph

    Crain, Steven P

    Crowley, Rebecca S

    Cuggia, Marc

    Curioso, Walter H

    de Coronado, Sherri

    de Richemond, Jeanette

    Del Fiol, Guilherme

    Demiris, George

    Demner-Fushman, Dina

    Deng, Xidong

    Denny, Joshua C

    Devine, Emily Beth

    Dexheimer, Judith W

    Dinakarpandian, Deendayal

    Dixon, Brian E

    Doan, Son

    Downey, Michael J

    Dreiseitl, Stephan

    Duke, Jon

    DuLong, Donna

    Durant, Kathleen

    DuVall, Scott L

    Dykes, Patricia C

    Ebadollahi, Shahram

    Edgerton, Mary

    Effken, Judith

    El Emam, Khaled

    Elhadad, Noemie

    Elhanan, Gai

    Elson, Robert

    Embi, Peter J

    Engelstad, Mark

    Erdal, Selnur

    Espino, Jeremy

    Evans, Scott

    Facelli, Julio

    Fan, Jung-Wei

    Feldman, Sue S

    Fenton, Susan H

    Fernandez-Breis, Jesualdo Tomas

    Ferraro, Jeffrey P

    Finnell, John

    Fiszman, Marcelo

    Franklin, Amy

    Frazier, Lorraine

    Frey, Lewis

    Fricton, James R

    Frisse, Mark E

    Fu, Lawrence

    Fung, Kin Wah

    Gadd, Cindy

    Gamache, Roland

    Garvin, Jennifer

    Gaynor, Mark

    Genes, Nicholas

    George, Sheba Mariam

    Georgiou, Andrew

    Gerber, Ben Steven

    Gershkovich, Peter

    Gesteland, Per Hans

    Gibb Kuttler, Kathryn

    Gong, Yang

    Grandison, Tyrone W A

    Grannis, Shaun

    Grasso, Michael A

    Gross, Ralph

    Guiney, Kathleen Marie

    Gundlapalli, Adi V

    Guo, Dongbai

    Hahn, Udo

    Hales, Joseph W

    Hall, Eric Scott

    Hammond, Kenric W

    Hammond, W Edward

    Hanauer, David A

    Haque, Saira

    Harkema, Henk

    Harpaz, Rave

    Harris, Marcelline R

    Harris, Paul

    Haug, Peter J

    Hawkins, Marla

    Heermann-Do, Kimberly Ann

    Hersh, William R

    Herskovic, Jorge R

    Hills, Rebecca

    Hodge, Chad

    Hogan, William

    Hogarth, Michael Andrew

    Hoggle, Lindsey

    Holbrook, Anne

    Holmes, John H

    Hongsermeier, Tonya

    Honour, Melissa

    Horsky, Jan

    Hristovski, Dimitar

    Hsiung, Robert

    Hsu, William

    Huang, Yang

    Huff, Stanley M

    Hulse, Nathan

    Hurdle, John

    Huser, Vojtech

    Hwang, Kevin

    Hyun, Sookyung

    Ibarra, Jesus

    Islamaj Dogan, Rezarta

    Jaffe, Conrade Carl

    Jalote-Parmar, Ashis

    Jao, Chiang

    Jaulent, Marie-Christine

    Jenkins, Melinda

    Johnson, Constance Margaret

    Johnson, Kevin

    Johnson, Stephen Bennett

    Johnson, Todd R

    Jones, Jason

    Kaelber, David Charles

    Kahn, Michael G

    Kahol, Kanav

    Kaiser, Katharina

    Kalpathy-Cramer, Jayashree

    Kantarcioglu, Murat

    Kao, Ming-Chih J

    Kaplan, Bonnie

    Kapusnik-Uner, Joan

    Karlsson, Daniel

    Karras, Bryant T

    Kaufman, David

    Kaushik, Sashank

    Kawamoto, Kensaku

    Keenan, Gail

    Khan, Sharib Ahmad

    Kidwai, Farah

    Kilbourne, John

    Kilbridge, Peter M

    Kilicoglu, Halil

    Kim, Hyeoneui

    Kim, Tae Youn

    Kluger, Yuval

    Knight, Amy

    Kohli, Manish

    Konovalov, Sergiy

    Koppel, Ross

    Kossman, Susan

    Koutkias, Vassilis

    Kroth, Philip J

    Kuperman, Gilad

    Kuziemsky, Craig

    Lai, Albert Max

    Lee, Eva K

    Lehmann, Christoph U

    Levin, James E

    Lewis, Bryan

    Li, Haiquan

    Li, Jianrong

    Liang, Jianming

    Lim, Tchoyoson Choie Cheio

    Lin, Chen Tan

    Linder, Jeffrey A

    Lipskiy, Nikolay

    Liu, Feifan

    Liu, Hongfang

    Liu, Lynda

    Livnat, Yarden

    Lober, William

    Logan, Judith R

    Lorenzi, Nancy M

    Lorenzi, Virginia

    Louie, Ben

    Lu, Zhiyong

    Luo, Zhihui

    Lyman, Jason

    Lytkin, Nikita

    Ma, Jingming

    Malin, Bradley

    Maloney, Christopher G

    Malousi, Andigoni

    Mamykina, Lena

    Mandl, Kenneth D

    Mani, Subramani

    Mar, Perry

    Marquard, Jenna

    Masanz, James J

    Massey, Tammara

    Mathe, Janos

    Matheny, Michael Edwin

    Matney, Susan A

    McClay, James

    McCormack, James

    McCray, Alexa

    McDaniel, Anna

    McInnes, D Keith

    Melton, Genevieve B

    Mendonca, Eneida

    Meric-Bernstam, Funda

    Meystre, Stephane

    Michel, George J

    Middleton, Blackford

    Miksch, Silvia

    Moen, Anne

    Mohrer, Daniel

    Moore, Carlton Reid

    Morgan, Alex

    Moritz, Michael L

    Mougin, Fleur

    Murphy, Daniel Robert

    Murphy, Robert

    Murphy, Shawn

    Musen, Mark

    Myneni, Sahiti

    Nachimuthu, Senthil K

    Nadkarni, Prakash

    Narus, Scott P

    Natarajan, Karthik

    Nebeker, Jonathan

    Nelson, Stuart J

    Neri, Pamela Michelle

    Neveol, Aurelie

    Nho, Kwangsik

    Nkoy, Flory L

    Novak, Laurie L

    OConnor, Martin Joseph

    Oemig, Frank

    Olsen, Joanne

    Otero, Carlos Martin

    Overhage, Marc

    Ownby, Raymond L

    Ozeran, Larry

    Ozkaynak, Mustafa

    Pacheco, Edson Jose

    Painter, Ian

    Pakhomov, Serguei

    Palchuk, Matvey B

    Palm, Jean-Marc

    Pan, Eric Chungren

    Patel, Chintan

    Patel, Chintan Odhavji

    Patel, Vaishali

    Patel, Vimla

    Paterno, Marilyn D

    Patrick, Jon

    Payne, Philip Richard Orrin

    Pedersen, Ted

    Peek, Niels

    Peleg, Mor

    Pelikan, Richard Craig

    Petersen, Carolyn

    Peterson, Josh F

    Petitti, Diana B

    Phansalkar, Shobha

    Phillips, Kirk T

    Poikonen, John

    Porcelli, Peter J

    Poynton, Mollie

    Pratt, Wanda

    Price, Ronald Charles

    Qi, Xiaopeng

    Rabadan, Raul

    Ralston, James

    Rector, Alan L

    Reid, Jon

    Resetar, Ervina

    Reynoso, Guillermo

    Riben, Michael

    Richards, Janise

    Richardson, Joshua E

    Richesson, Rachel Lynn

    Rindflesch, Thomas

    Rindflesh, Thomas

    Rodriquez Gonzalez, David

    Rose, Eric

    Rosenbloom, Samuel Trent

    Ross, Stephen Eisenhard

    Rothschild, Jeffrey Mark

    Roudsari, Abdul Vahabpour

    Rubin, Daniel L

    Ruch, Patrick

    Rudniy, Alex

    Safran, Charles

    Saleem, Jason J

    Samal, Lipika

    Sanderson, Penelope Margaret

    Sapci, Hasan

    Sarcevic, Aleksandra

    Sarkar, Indra Neil

    Schiff, Gordon

    Schilling, Lisa

    Schulz, Stefan

    Scotch, Matthew

    Sellen, Katherine M

    Senathirajah, Yalini

    Senior, Andrew

    Senjem, Matt

    Shabo, Amnon

    Shah, Nigam H

    Shahar, Yuval

    Shalaby, James

    Shapiro, Jason

    Shaw, Nicola

    Shea, Kimberly

    Showalter, John W

    Shultz, Edward

    Silverstein, Jonathan C

    Simonaitis, Linas

    Sims, Shannon

    Slavkovich, Aleksandra

    Smith, Barry

    Smith, Catherine Arnott

    Smith, Phillip Ross

    Sohn, Sunghwan

    Solbrig, Harold

    Solti, Imre

    South, Brett R

    Spackman, Kent

    Spallek, Heiko

    Speedie, Stuart

    Spronk, Rene

    Spyropoulos, Basile

    Srinivasan, Suresh

    Staes, Catherine

    Staggers, Nancy

    Starren, Justin

    Statnikov, Alexander

    Stausberg, Jrgen

    Stephan, Christina Lynn

    Strasberg, Howard R

    Strong, Diane

    Sun, Jimeng

    Sward, Katherine A

    Syed, Zeeshan

    Syeda-Mahmood, Tanveer

    Taboada, Manel

    Talbert, Doug

    Tandon, Sanjeev

    Tang, Paul

    Tang, Zuojian

    Tao, Cui

    Tao, Donghua

    Tate, Anne Rosemary

    Taylor, Laura

    Thomas, Sean

    Thornton, Sidney

    Thyvalikakath, Thankam P

    Tolentino, Herman

    Tong, Tuanjie

    Topaloglu, Umit

    Torres-Urquidy, Miguel Humberto

    Travers, Debbie A

    Triola, Marc

    Tripp, Jacob S

    Trusko, Brett E

    Tu, Samson W

    Tudorache, Tania

    Turchin, Alexander

    Unertl, Kim

    Uzuner, Ozlem

    Valdez, Ignacio

    van Mulligen, Erik M

    Varga, John

    Varn, Dowman Parks

    Vawdrey, David

    Verspoor, Karin

    Vimarlund, Vivian

    Visweswaran, Shyam

    Vreeman, Daniel Jay

    Wagener, Diane

    Wahi, Monika Maya

    Waitman, Lemuel Russ

    Walji, Muhammad F

    Walson, Judd

    Wang, Jinhua

    Wang, Lu

    Wantland, Dean

    Warren, Judith J

    Wehbe, Firas

    Weinberg, Stuart T

    Weiner, Mark

    Weir, Charlene

    Welch, Susan

    Weng, Chunhua

    Were, Martin C

    Westra, Bonnie

    Whipple, Nancy Nasuti

    Wilbur, W John

    Wilcox, Adam

    Xu, Hua

    Xu, Wu

    Yang, Jianji

    Yoshida, Eileen

    Yu, Hong

    Zeng, Kelly

    Zeng-Treitler, Qing

    Zhang, Dongming

    Zhang, GQ

    Zhang, Jun

    Zhang, Songmao

    Zhao, Tian

    Zheng, Kai

    Zhou, Li

    Zuccotti, Gianna

    Zweigenbaum, Pierre
  • AMIA 2010 Scientific Program Committee (SPC) AMIA 2010 Scientific Program Committee (SPC)
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    AMIA 2010 Scientific Program Committee (SPC)

    Gil Kuperman, AMIA 2010 Chair
    New York-Presbyterian Hospital, Columbia University, and Weill-Cornell Medical College

    Carol Friedman, AMIA 2010 Vice Chair
    Columbia University

    Dean F. Sittig, AMIA 2010 Vice Chair
    University of Texas School of Health Information Sciences at Houston

    R. Scott Evans, AMIA 2011 Chair
    LDS Hospital, Intermountain Healthcare, and University of Utah

    Michael J. Ackerman
    National Library of Medicine

    Joan Ash
    Oregon Health & Science University

    Elmer V. Bernstam
    University of Texas School of Health Information Sciences at Houston

    Olivier Bodenreider
    National Library of Medicine

    Cynthia Brandt
    Yale University

    Elizabeth Chen
    University of Vermont

    Rebecca Crowley
    University of Pittsburgh

    Noemie Elhadad
    Columbia University

    Michael A. Grasso
    University of Maryland School of Medicine

    Marcelline R. Harris
    Mayo Clinic

    Peter Haug
    University of Utah

    Nathan Hulse
    University of Utah

    Robert A. Jenders
    University of California, Los Angeles

    Bonnie Kaplan
    Yale University and Kaplan Associates

    David Kaufman
    Columbia University

    Ken Kawamoto
    Duke University

    Rita Kukafka
    Columbia University

    Casimir Kulikowski
    Rutgers University

    Christoph U. Lehmann
    Johns Hopkins University and American Academy of Pediatrics

    Jeffrey A. Linder
    Brigham and Women’s Hospital, Harvard Medical School, and Partners Healthcare

    William Lober
    University of Washington

    Yves Lussier
    University of Chicago

    Brad Malin
    Vanderbilt University

    Thomas Payne
    University of Washington

    Mary Reagan, Nurse Planner
    University of Maryland School of Nursing

    Steve Ross
    University of Colorado

    Jason Saleem
    Regenstrief Institute, Inc., Richard L. Roudebush VA Medical Center, and Indiana University-Purdue University Indianapolis

    Stefan Schulz
    University Medical Center Freiburg

    Yuval Shahar
    Ben-Gurion University of the Negev

    Alexander Statnikov
    New York University

    Adam Wilcox
    Columbia University

    Adam Wright
    Brigham and Women’s Hospital and Harvard Medical School
  • 2010 AMIA Board of Directors 2010 AMIA Board of Directors
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    AMIA Board of Directors

     

    Officers

    Chair
    Nancy M. Lorenzi
    Vanderbilt University Medical Center
    Nashville, TN
    (2010-2011)

    Past Chair
    David W. Bates
    Brigham and Women’s Hospital
    Boston, MA
    (2010)

    AMIA President and CEO
    Edward H. Shortliffe
    Bethesda, MD

    Secretary
    Christoph U. Lehmann
    Johns Hopkins Children's Medical and Surgical Center
    Johns Hopkins University School of Medicine
    Baltimore, MD
    (2010-2011)

    Treasurer
    R. Scott Evans
    LDS Hospital
    Intermountain Health Care
    Salt Lake City, UT
    (2010-2011)
     

    Directors

    Dominik Aronsky
    Vanderbilt University
    Nashville, TN
    (2008-2010)

    Eta S. Berner
    University of Alabama at Birmingham
    Birmingham, AL
    (2010-2012)

    Atul J. Butte
    Stanford University School of Medicine
    Stanford, CA
    (2009-2011)

    Helen Burstin
    National Quality Forum
    Washington, DC
    (2008-2010)

    Connie J. Delaney
    University of Minnesota School of Nursing
    Minneapolis, MN
    (2009-2011)

    John H. Holmes
    University of Pennsylvania
    Philadelphia, PA
    (2010-2012)

    Kevin B. Johnson
    Vanderbilt University Medical Center
    Nashville, TN
    (2008-2010)

    Rita Kukafka
    Columbia University
    New York, NY
    (2008-2010)

    Gilad J. Kuperman
    New York Presbyterian Hospital
    New York, NY
    (2009-2011)

    Blackford Middleton
    Partners HealthCare
    Harvard Medical School
    Boston, MA
    (2009-2011)

    Justin B. Starren
    Marshfield Clinic Research Foundation
    Marshfield, WI
    (2010-2012)

    Bonnie L. Westra
    University of Minnesota School of Nursing
    Minneapolis, MN
    (2010-2012)

     

    Ex-Officio Board Members

    American College of Medical Informatics
    President
    Joyce A. Mitchell
    University of Utah
    Salt Lake City, UT
    (2009-2010)

    Student WG Representative
    David C. Kaelber
    Case Western Reserve University
    Shaker Heights, OH
    (2010-2011)
  • 2010 Author Index 2010 Author Index
  • Preface Preface
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    Preface

    I want to thank you for taking the time to attend the 2010 AMIA Annual Symposium, the premier venue for the exchange of ideas in informatics.

    The opportunity for informatics to contribute to improvements in health has never been greater.  Government programs have created incentives for physicians and hospitals to adopt electronic health records.  Also, as the amount of available electronic clinical data is increasing, computational techniques are being developed to mine data for knowledge, parse nature language for coded concepts, and combine genetic data with phenotypic data.  However, there are many questions for the informatics community to grapple with, including:  how to implement EHRs effectively and safely, how to evolve EHRs over time so even greater benefits can be realized, how to develop an adequate informatics workforce for the nation, how to support comparative effectiveness and other kinds of research and how to best apply the techniques of computer science to the vast amounts of available electronic data.  This year’s Symposium includes 192 papers, 29 panels, 10 demonstrations, 4 partnerships, 11 workshops, 30 tutorials and 10 invited sessions that cover work in both the applied and foundational aspects of informatics.

    We are privileged to have two keynote speakers at this conference.  Susan Dentzer is the Editor-in-Chief of Health Affairs, the nation’s foremost health policy journal, and a past health correspondent for the McNeil-Lehrer News Hour.  Ms. Dentzer will share her insights regarding important national and international health policy challenges and ways that informatics can help address those problems.  David Blumenthal, MD, is the National Coordinator for Health Information Technology.  His office is overseeing the development of the “meaningful use” policy that guides the incentive funding for EHRs in the United States, as well as programs to support EHR adoption, informatics research and development, and informatics workforce development.  Dr. Blumenthal’s comments will give us an insight into future directions of the government programs and the ways that informatics can play a role.

    In addition to the submitted content and the keynote speakers, the Symposium also features invited sessions on a variety of topics including the relationship of computer science to informatics, the ONC SHARP research and development program, the relevance of informatics to CMIOs, nursing informatics to support the continuum of care, global health informatics, as well as the ever-popular Informatics Year in Review.

    This year, for the first time, the conference proceedings will be available online and will even be available in advance of the conference.

    I want to thank the 30 members of this year’s Scientific Program Committee who helped oversee the editorial review process that created the Symposium’s submitted content.  And I want to thank the two Track Chairs, Carol Friedman and Dean Sittig, who helped me admirably with the planning of the Symposium.  I also want to thank the AMIA staff, especially the AMIA VP for Education, Jeff Williamson, for supporting the committee and bringing the Symposium to fruition. 

    Most of all I want to express my appreciation to the 504 reviewers who reviewed and made comments on the submitted content.  The quality of the Symposium is directly related to the quality of the work done by the reviewers, so I gratefully recognize their efforts.

    I wish you a successful conference and hope you find information that will bring benefit to your organization and your community.

     

    Gil Kuperman
    AMIA 2010 Scientific Program Committee Chair
    New York-Presbyterian Hospital, Columbia University, and Weill-Cornell Medical College
  • Notice Notice
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    NOTICE

    Medicine is an ever-changing science. As new research and clinical experience broaden our knowledge, changes in treatment and drug therapy are required. The authors and the publishers of this work have checked with sources believed to be reliable in their efforts to provide information that is complete and generally in accord with the standards accepted at the time of publication. However, in view of the possibility of human error or changes in medical sciences, neither the authors nor the publisher nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they are not responsible for any errors or omissions or for the results obtained from use of such information. Readers are encouraged to confirm the information contained herein with other sources. For example and in particular, readers are advised to check the product information sheet included in the package of each drug they plan to administer to be certain that the information contained in this book is accurate and that changes have not been made in recommended dose or in the contraindication for administration. This recommendation is of particular importance in connection with new or infrequently used drugs.

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